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Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors.

The U1 snRNP-specific 70K protein is one of the few snRNP proteins from higher eukaryotic cells that is phosphorylated in vivo (1,2). Immunoaffinity purified spliceosomal snRNPs (U1, U2, U5, and U4/U6) were tested for their ability to phosphorylate in vitro the U1-specific 70K protein. An snRNP-asso...

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Main Authors: Woppmann, A, Will, C L, Kornstädt, U, Zuo, P, Manley, J L, Lührmann, R
Format: Artigo
Jezik:Inglês
Izdano: 1993
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC309659/
https://ncbi.nlm.nih.gov/pubmed/8332490
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