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Arginine Deprivation as a Targeted Therapy for Cancer

Certain cancers may be auxotrophic for a particular amino acid and amino acid deprivation is one method to treat these tumors. Arginine deprivation is a novel approach to target tumors which lack argininosuccinate synthetase (ASS) expression. ASS is a key enzyme which converts citrulline to arginine...

詳細記述

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書誌詳細
主要な著者: Feun, L., You, M., Wu, C.J., Kuo, M.T., Wangpaichitr, M., Spector, S., Savaraj, N.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096551/
https://ncbi.nlm.nih.gov/pubmed/18473854
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