Endogenous Matrix Metalloproteinases 2 and 9 Regulate Activation of CD4(+) and CD8(+) T cells

We reported that inhibiting matrix metalloproteinases (MMP), known to remodel the extracellular matrix, also down-regulated antigen-specific T-cell responses. However, the direct role of MMP2 and MMP9 in regulating intracellular function in T cells is unknown. Markers of cellular activation and cyto...

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Main Authors: Benson, Heather L., Mobashery, Shahriar, Chang, Mayland, Kheradmand, Farrah, Hong, Jeong Soo, Smith, Gerald N., Shilling, Rebecca A., Wilkes, David S.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095987/
https://ncbi.nlm.nih.gov/pubmed/20639459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0125OC
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