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MiR-146b-5p suppresses EGFR expression and reduces in vitro migration and invasion of glioma

Human miR-146b-5p is located on chromosome 10q24.3. Loss of the 10q24-26 region is frequently observed in gliomas. Here, we report that miR-146b-5p suppresses expression of epidermal growth factor receptor (EGFR) in human glioblastoma cell lines. Introduction of miR-146b-5p decreases cell invasion,...

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Detalhes bibliográficos
Main Authors: Katakowski, Mark, Zheng, Xuguang, Jiang, Feng, Rogers, Thomas, Szalad, Alexandra, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095944/
https://ncbi.nlm.nih.gov/pubmed/20874002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07357907.2010.512596
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