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hTID-1 defines a novel regulator of c-Met Receptor signaling in renal cell carcinomas
The c-Met receptor tyrosine kinase (MetR) is frequently overexpressed and constitutively phosphorylated in a number of human malignancies. Activation of the receptor by its ligand, hepatocyte growth factor (HGF), leads to increased cell proliferation, motility, survival and disruption of adherens ju...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095899/ https://ncbi.nlm.nih.gov/pubmed/21242965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.601 |
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