hTID-1 defines a novel regulator of c-Met Receptor signaling in renal cell carcinomas

The c-Met receptor tyrosine kinase (MetR) is frequently overexpressed and constitutively phosphorylated in a number of human malignancies. Activation of the receptor by its ligand, hepatocyte growth factor (HGF), leads to increased cell proliferation, motility, survival and disruption of adherens ju...

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Bibliographic Details
Main Authors: Copeland, E, Balgobin, S, Lee, C M, Rozakis-Adcock, M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095899/
https://ncbi.nlm.nih.gov/pubmed/21242965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.601
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