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Disease Risk of Missense Mutations Using Structural Inference from Predicted Function

Advancements in sequencing techniques place personalized genomic medicine upon the horizon, bringing along the responsibility of clinicians to understand the likelihood for a mutation to cause disease, and of scientists to separate etiology from nonpathologic variability. Pathogenicity is discernabl...

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Hlavní autoři: Horst, Jeremy A., Wang, Kai, Horst, Orapin V., Cunningham, Michael L., Samudrala, Ram
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095817/
https://ncbi.nlm.nih.gov/pubmed/20887259
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