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Diversity of protein structures and difficulties in fold recognition: the curious case of protein G
We examine the ability of current state-of-the-art methods in protein structure prediction to discriminate topologically distant folds encoded by highly similar (>90% sequence identity) designed proteins in blind protein structure prediction experiments. We detail the corresponding prognosis for...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Biology Reports Ltd
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832337/ https://ncbi.nlm.nih.gov/pubmed/20209018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-69 |
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