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Tyrosine kinase inhibitors: Multi-targeted or single-targeted?
Since in most tumors multiple signaling pathways are involved, many of the inhibitors in clinical development are designed to affect a wide range of targeted kinases. The most important tyrosine kinase families in the development of tyrosine kinase inhibitors are the ABL, SCR, platelet derived growt...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095472/ https://ncbi.nlm.nih.gov/pubmed/21603317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v2.i2.80 |
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