The M. tuberculosis Phosphate-Binding Lipoproteins PstS1 and PstS3 Induce Th1 and Th17 Responses That Are Not Associated with Protection against M. tuberculosis Infection

The M. tuberculosis phosphate-binding transporter lipoproteins PstS1 and PstS3 were good immunogens inducing CD8(+) T-cell activation and both Th1 and Th17 immunity in mice. However, this antigen-specific immunity, even when amplified by administration of the protein with the adjuvant LTK63 or by th...

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Bibliographische Detailangaben
Hauptverfasser: Palma, Carla, Spallek, Ralf, Piccaro, Giovanni, Pardini, Manuela, Jonas, Fatima, Oehlmann, Wulf, Singh, Mahavir, Cassone, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095447/
https://ncbi.nlm.nih.gov/pubmed/21603219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/690328
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