Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis

TMEM106B has recently been identified as a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic lateral sclerosis (ALS), like FTLD-TDP, is characterized by pathological TDP-43 inclusions. We therefore investigated whether FTLD-TDP-associated risk g...

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Autores principales: Vass, Ryan, Ashbridge, Emily, Geser, Felix, Hu, William T., Grossman, Murray, Clay-Falcone, Dana, Elman, Lauren, McCluskey, Leo, Lee, Virginia M. Y., Van Deerlin, Vivianna M., Trojanowski, John Q., Chen-Plotkin, Alice S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095217/
https://ncbi.nlm.nih.gov/pubmed/21104415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0782-y
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