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Cancer immunotherapy using a bi-specific NK receptor- fusion protein that engages both T cells and tumor cells

T cell immunotherapy is a promising strategy to treat cancer. The aim of this study was to investigate a new approach to deliver selective T cell activation against tumor cells. We have developed a bi-specific fusion protein that recognizes tumor cells through an NK activating receptor NKG2D and sti...

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Bibliografiske detaljer
Main Authors: Zhang, Tong, Sentman, Charles L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095211/
https://ncbi.nlm.nih.gov/pubmed/21282338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3200
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