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Prespliceosomal Assembly on Microinjected Precursor mRNA Takes Place in Nuclear Speckles

Nuclear speckles (speckles) represent a distinct nuclear compartment within the interchromatin space and are enriched in splicing factors. They have been shown to serve neighboring active genes as a reservoir of these factors. In this study, we show that, in HeLa cells, the (pre)spliceosomal assembl...

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Autori principali: Melčák, Ivo, Melčáková, Štěpánka, Kopsky, Vojtěch, Večeřová, Jaromíra, Raška, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC30951/
https://ncbi.nlm.nih.gov/pubmed/11179423
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