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Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation
Pre-mRNA splicing is catalyzed by the large ribonucleoprotein spliceosome. Spliceosome assembly is a highly dynamic process in which the complex transitions through a number of intermediates. Recently, the potent anti-tumor compound Spliceostatin A (SSA) was shown to inhibit splicing and to interact...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965229/ https://ncbi.nlm.nih.gov/pubmed/20529876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq494 |
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