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Anticancer activity of Noscapine, an opioid alkaloid in combination with Cisplatin in human non-small cell lung cancer

The purpose of this study was to examine the efficacy of Noscapine (Nos) and Cisplatin (Cis) combination treatment in vitro in A549 and H460 lung cancer cells, in vivo in murine xenograft model and to investigate the underlying mechanism. The combination index values (<0.6) suggested synergistic...

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Autors principals: Chougule, Mahavir, Patel, Apurva R., Sachdeva, Pratik, Jackson, Tanise, Singh, Mandip
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094914/
https://ncbi.nlm.nih.gov/pubmed/20674069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2010.06.002
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