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Peptide conformational preferences in osmolyte solutions: Transfer free energies of deca-alanine
The nature in which the protecting osmolyte trimethylamine-N-oxide (TMAO) and the denaturing osmolyte urea affect protein stability is investigated simulating a deca-alanine peptide model in multiple conformations of the denatured ensemble. Binary solutions of both osmolytes and mixed osmolyte solut...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094602/ https://ncbi.nlm.nih.gov/pubmed/21250690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1078128 |
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