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CONTROLLING COAGULATION DYSREGULATION IN XENOTRANSPLANTATION

PURPOSE OF REVIEW: Deletion of the α1,3-galactosyltransferase (GalT) gene in pigs has removed a major xenoantigen but has not eliminated the problem of dysregulated coagulation and vascular injury. Rejecting GalT KO organ xenografts almost invariably show evidence of thrombosis and platelet sequestr...

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Bibliographic Details
Main Authors: Cowan, Peter J., Robson, Simon C., d’Apice, Anthony J.F.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094512/
https://ncbi.nlm.nih.gov/pubmed/21415824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOT.0b013e3283446c65
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