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COAGULATION DYSREGULATION AS A BARRIER TO XENOTRANSPLANTATION IN THE PRIMATE

PURPOSE OF REVIEW: The ability to generate pigs expressing a human complement regulatory protein (hCRP) and/or pigs in which the α1,3-galactosyltransferase gene has been knocked out (GT-KO) has largely overcome the barrier of hyperacute rejection of a pig organ transplanted into a primate. However,...

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Autors principals: Lin, Chih Che, Cooper, David K.C., Dorling, Anthony
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757551/
https://ncbi.nlm.nih.gov/pubmed/19000927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2008.10.008
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