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Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity

One goal of aging research is to develop interventions that combat age-related illnesses and slow aging. Although numerous mutations have been shown to achieve this in various model organisms, only a handful of chemicals have been identified to slow aging. Here we report that celecoxib, a non-steroi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ching, Tsui-Ting, Chiang, Wei-Chung, Chen, Ching-Shih, Hsu, Ao-Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094508/
https://ncbi.nlm.nih.gov/pubmed/21348927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00688.x
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