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A complex containing DDL-1 and HSF-1 links insulin-like signaling to heat-shock response in C. elegans
Extended longevity is often correlated with increased resistance against various stressors. Insulin/IGF-1-like signaling (IIS) is known to have a conserved role in aging and cellular mechanisms against stress. In C. elegans, genetic studies suggest that heat-shock transcription factor HSF-1 is requi...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615449/ https://ncbi.nlm.nih.gov/pubmed/22265419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.12.019 |
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