Epigenetic Alterations in Liver of C57BL/6J Mice after Short-Term Inhalational Exposure to 1,3-Butadiene

BACKGROUND: 1,3-Butadiene (BD) is a high-volume industrial chemical and a known human carcinogen. The main mode of BD carcinogenicity is thought to involve formation of genotoxic epoxides. OBJECTIVES: In this study we tested the hypothesis that BD may be epigenotoxic (i.e., cause changes in DNA and...

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Autors principals: Koturbash, Igor, Scherhag, Anne, Sorrentino, Jessica, Sexton, Kenneth, Bodnar, Wanda, Tryndyak, Volodymyr, Latendresse, John R., Swenberg, James A., Beland, Frederick A., Pogribny, Igor P., Rusyn, Ivan
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094413/
https://ncbi.nlm.nih.gov/pubmed/21147608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002910
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