VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation

BACKGROUND: Aortic stenosis (AS) affects 3 percent of persons older than 65 years and leads to greater morbidity and mortality than other cardiac valve diseases. Surgery with aortic valve replacement (AVR) for severe symptomatic AS is currently the only treatment option. Unfortunately, in patients w...

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Main Authors: Xu, Xiao H, Xu, Jing, Xue, Lei, Cao, Hai L, Liu, Xiang, Chen, Yi J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094376/
https://ncbi.nlm.nih.gov/pubmed/21496294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-6-54
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