Artesunate Dose Escalation for the Treatment of Uncomplicated Malaria in a Region of Reported Artemisinin Resistance: A Randomized Clinical Trial

BACKGROUND: The emergence of artemisinin resistance has raised concerns that the most potent antimalarial drug may be under threat. The currently recommended daily dose of artesunate (AS) is 4 mg/kg, and is administered for 3 days together with a partner antimalarial drug. This study investigated th...

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Detalhes bibliográficos
Main Authors: Bethell, Delia, Se, Youry, Lon, Chanthap, Tyner, Stuart, Saunders, David, Sriwichai, Sabaithip, Darapiseth, Sea, Teja-Isavadharm, Paktiya, Khemawoot, Phisit, Schaecher, Kurt, Ruttvisutinunt, Wiriya, Lin, Jessica, Kuntawungin, Worachet, Gosi, Panita, Timmermans, Ans, Smith, Bryan, Socheat, Duong, Fukuda, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094355/
https://ncbi.nlm.nih.gov/pubmed/21603629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019283
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