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Deletion of Dlx1 results in reduced glutamatergic input to hippocampal interneurons

Dlx transcription factors are important in the differentiation of GABAergic interneurons. In mice lacking Dlx1, early steps in interneuron development appear normal. Beginning at ∼1 mo of age, primarily dendrite-innervating interneuron subtypes begin to undergo apoptosis in Dlx1(−/−) mice; this is a...

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Detalhes bibliográficos
Main Authors: Jones, Daniel L., Howard, MacKenzie A., Stanco, Amelia, Rubenstein, John L. R., Baraban, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094166/
https://ncbi.nlm.nih.gov/pubmed/21325686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00056.2011
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