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Deletion of Dlx1 results in reduced glutamatergic input to hippocampal interneurons

Dlx transcription factors are important in the differentiation of GABAergic interneurons. In mice lacking Dlx1, early steps in interneuron development appear normal. Beginning at ∼1 mo of age, primarily dendrite-innervating interneuron subtypes begin to undergo apoptosis in Dlx1(−/−) mice; this is a...

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Bibliografiske detaljer
Main Authors: Jones, Daniel L., Howard, MacKenzie A., Stanco, Amelia, Rubenstein, John L. R., Baraban, Scott C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094166/
https://ncbi.nlm.nih.gov/pubmed/21325686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00056.2011
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