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Glial cell line–derived neurotrophic factor receptor–alpha 1 expressed in striatum in trans regulates development and injury response of dopamine neurons of the substantia nigra

Many of the cellular effects of glial cell line-derived neurotrophic factor are initiated by binding to GNDF family receptor alpha-1 (GFRα1), and mediated by diverse intracellular signaling pathways, most notably through the Ret tyrosine kinase. Ret may be activated by the cell autonomous expression...

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Autores principales: Kholodilov, Nikolai, Kim, Sang Ryong, Yarygina, Olga, Kareva, Tatyana, Cho, Jin Whan, Baohan, Amy, Burke, Robert E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094150/
https://ncbi.nlm.nih.gov/pubmed/21133924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.07128.x
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