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Evidence that metabolism and chromosome copy number control mutually exclusive cell fates in Bacillus subtilis

Bacillus subtilis chooses between matrix production and spore formation, which are both controlled by the regulator Spo0A∼P. We report that metabolism and chromosome copy number dictate which fate is adopted. Conditions that favour low Spo0A∼P levels promote matrix production, whereas conditions fav...

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Detalhes bibliográficos
Main Authors: Chai, Yunrong, Norman, Thomas, Kolter, Roberto, Losick, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094124/
https://ncbi.nlm.nih.gov/pubmed/21326214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.36
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