A mathematical model of spontaneous calcium release in cardiac myocytes

In cardiac myocytes, calcium (Ca) can be released from the sarcoplasmic reticulum independently of Ca influx from voltage-dependent membrane channels. This efflux of Ca, referred to as spontaneous Ca release (SCR), is due to Ryanodine receptor fluctuations, which can induce spontaneous Ca sparks, wh...

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Bibliographic Details
Main Authors: Chen, Wei, Aistrup, Gary, Wasserstrom, J. Andrew, Shiferaw, Yohannes
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
Subjects:
Cardiac Excitation and Contraction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094092/
https://ncbi.nlm.nih.gov/pubmed/21357507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01121.2010
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