Thermodynamic stability and drug-binding properties of oligodeoxyribonucleotide duplexes containing 3-deazaadenine:thymine base pairs.

We have used ultraviolet melting techniques to study the effect on stability of incorporating the nucleoside analogue 2'-deoxy-3-deazaadenosine (d3cA) into the duplex 5'-d(CGCAATCG)-3'-d(GCGTTAGC). Our results demonstrate that the successive replacement of dA by d3CA increasingly dest...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lever, C, Li, X, Cosstick, R, Ebel, S, Brown, T
Format: Artigo
Idioma:Inglês
Publicat: 1993
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC309409/
https://ncbi.nlm.nih.gov/pubmed/8493091
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars