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Synthetic conversion of a graded receptor signal into a tunable, reversible switch

The ability to engineer an all-or-none cellular response to a given signaling ligand is important in applications ranging from biosensing to tissue engineering. However, synthetic gene network ‘switches' have been limited in their applicability and tunability due to their reliance on specific c...

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Detalhes bibliográficos
Main Authors: Palani, Santhosh, Sarkar, Casim A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094063/
https://ncbi.nlm.nih.gov/pubmed/21451590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.13
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