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Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity

The mechanisms for increased risk of chronic kidney disease (CKD) in obesity remain unclear. The renin-angiotensin system is implicated in the pathogenesis of both adiposity and CKD. We investigated whether the angiotensin type 1 (AT(1)) receptor, composed of dominant AT(1a) and less expressed AT(1b...

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Bibliografiska uppgifter
Huvudupphovsmän: Ma, Li-Jun, Corsa, Bridgette A., Zhou, Jun, Yang, HaiChun, Li, HaiJing, Tang, Yi-Wei, Babaev, Vladimir R., Major, Amy S., Linton, MacRae F., Fazio, Sergio, Hunley, Tracy E., Kon, Valentina, Fogo, Agnes B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094053/
https://ncbi.nlm.nih.gov/pubmed/21367915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00468.2010
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