Depletion of tissue plasminogen activator attenuates lung ischemia-reperfusion injury via inhibition of neutrophil extravasation

Ischemia-reperfusion (IR) injury following lung transplantation remains a major source of early morbidity and mortality. Histologically, this inflammatory process is characterized by neutrophil infiltration and activation. We previously reported that lung IR injury was significantly attenuated in pl...

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Main Authors: Zhao, Yunge, Sharma, Ashish K., LaPar, Damien J., Kron, Irving L., Ailawadi, Gorav, Liu, Yuan, Jones, David R., Laubach, Victor E., Lau, Christine L.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094027/
https://ncbi.nlm.nih.gov/pubmed/21378024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00227.2010
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