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A model of chronic inflammation and pulmonary emphysema after multiple ozone exposures in mice

Oxidative stress plays a role in the pathophysiology of emphysema through the activation of tissue proteases and apoptosis. We examined the effects of ozone exposure by exposing BALB/c mice to either a single 3-h exposure or multiple exposures over 3 or 6 wk, with two 3-h exposures per week. Compare...

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Autors principals: Triantaphyllopoulos, Kostas, Hussain, Farhana, Pinart, Mariona, Zhang, Min, Li, Feng, Adcock, Ian, Kirkham, Paul, Zhu, Jie, Chung, Kian Fan
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094024/
https://ncbi.nlm.nih.gov/pubmed/21355040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00252.2010
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