Small GTPase Rab11b regulates degradation of surface membrane L-type Ca(v)1.2 channels

L-type Ca(2+) channels (LTCCs) play a critical role in Ca(2+)-dependent signaling processes in a variety of cell types. The number of functional LTCCs at the plasma membrane strongly influences the strength and duration of Ca(2+) signals. Recent studies demonstrated that endosomal trafficking provid...

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Bibliographic Details
Main Authors: Best, Jabe M., Foell, Jason D., Buss, Courtney R., Delisle, Brian P., Balijepalli, Ravi C., January, Craig T., Kamp, Timothy J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
Subjects:
Membrane Transporters, Ion Channels and Pumps
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093944/
https://ncbi.nlm.nih.gov/pubmed/21248079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00288.2010
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