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A Multi-domain Fragment of Nogo-A Protein Is a Potent Inhibitor of Cortical Axon Regeneration via Nogo Receptor 1

Nogo-A limits axon regeneration and functional recovery after central nervous system injury in adult mammals. Three regions of Nogo-A (Nogo-A-24, Nogo-66, and Nogo-C39) interact with the neuronal Nogo-66 receptor 1 (NgR1). Nogo-66 also interacts with a structurally unrelated cell surface receptor, p...

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Detalhes bibliográficos
Main Authors: Huebner, Eric A., Kim, Byung G., Duffy, Philip J., Brown, Rebecca H., Strittmatter, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093876/
https://ncbi.nlm.nih.gov/pubmed/21454605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208108
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