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DDR1 Receptor Tyrosine Kinase Promotes Prosurvival Pathway through Notch1 Activation

DDR1 (discoidin domain receptor tyrosine kinase 1) kinase is highly expressed in a variety of human cancers and occasionally mutated in lung cancer and leukemia. It is now clear that aberrant signaling through the DDR1 receptor is closely associated with various steps of tumorigenesis, although litt...

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Bibliografiske detaljer
Main Authors: Kim, Hyung-Gu, Hwang, So-Young, Aaronson, Stuart A., Mandinova, Anna, Lee, Sam W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093843/
https://ncbi.nlm.nih.gov/pubmed/21398698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236612
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