Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance

Monoglyceride lipase (MGL) influences energy metabolism by at least two mechanisms. First, it hydrolyzes monoacylglycerols (MG) into fatty acids and glycerol. These products can be used for energy production or synthetic reactions. Second, MGL degrades 2-arachidonoyl glycerol (2-AG), the most abunda...

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Autori principali: Taschler, Ulrike, Radner, Franz P. W., Heier, Christoph, Schreiber, Renate, Schweiger, Martina, Schoiswohl, Gabriele, Preiss-Landl, Karina, Jaeger, Doris, Reiter, Birgit, Koefeler, Harald C., Wojciechowski, Jacek, Theussl, Christian, Penninger, Josef M., Lass, Achim, Haemmerle, Guenter, Zechner, Rudolf, Zimmermann, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093820/
https://ncbi.nlm.nih.gov/pubmed/21454566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215434
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