Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance

Monoglyceride lipase (MGL) influences energy metabolism by at least two mechanisms. First, it hydrolyzes monoacylglycerols (MG) into fatty acids and glycerol. These products can be used for energy production or synthetic reactions. Second, MGL degrades 2-arachidonoyl glycerol (2-AG), the most abunda...

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Hlavní autoři: Taschler, Ulrike, Radner, Franz P. W., Heier, Christoph, Schreiber, Renate, Schweiger, Martina, Schoiswohl, Gabriele, Preiss-Landl, Karina, Jaeger, Doris, Reiter, Birgit, Koefeler, Harald C., Wojciechowski, Jacek, Theussl, Christian, Penninger, Josef M., Lass, Achim, Haemmerle, Guenter, Zechner, Rudolf, Zimmermann, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093820/
https://ncbi.nlm.nih.gov/pubmed/21454566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215434
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