Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance

Monoglyceride lipase (MGL) influences energy metabolism by at least two mechanisms. First, it hydrolyzes monoacylglycerols (MG) into fatty acids and glycerol. These products can be used for energy production or synthetic reactions. Second, MGL degrades 2-arachidonoyl glycerol (2-AG), the most abunda...

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Autores principales: Taschler, Ulrike, Radner, Franz P. W., Heier, Christoph, Schreiber, Renate, Schweiger, Martina, Schoiswohl, Gabriele, Preiss-Landl, Karina, Jaeger, Doris, Reiter, Birgit, Koefeler, Harald C., Wojciechowski, Jacek, Theussl, Christian, Penninger, Josef M., Lass, Achim, Haemmerle, Guenter, Zechner, Rudolf, Zimmermann, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093820/
https://ncbi.nlm.nih.gov/pubmed/21454566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215434
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