Monoglyceride Lipase Deficiency in Mice Impairs Lipolysis and Attenuates Diet-induced Insulin Resistance

Monoglyceride lipase (MGL) influences energy metabolism by at least two mechanisms. First, it hydrolyzes monoacylglycerols (MG) into fatty acids and glycerol. These products can be used for energy production or synthetic reactions. Second, MGL degrades 2-arachidonoyl glycerol (2-AG), the most abunda...

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Main Authors: Taschler, Ulrike, Radner, Franz P. W., Heier, Christoph, Schreiber, Renate, Schweiger, Martina, Schoiswohl, Gabriele, Preiss-Landl, Karina, Jaeger, Doris, Reiter, Birgit, Koefeler, Harald C., Wojciechowski, Jacek, Theussl, Christian, Penninger, Josef M., Lass, Achim, Haemmerle, Guenter, Zechner, Rudolf, Zimmermann, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093820/
https://ncbi.nlm.nih.gov/pubmed/21454566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.215434
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