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Hypervalent Organochalcogenanes as Inhibitors of Protein Tyrosine Phosphatases
A series of organochalcogenanes was synthesized and evaluated as protein tyrosine phosphatases (PTPs) inhibitors. The results indicate that organochalcogenanes inactivate the PTPs in a time- and concentration-dependent fashion, most likely through covalent modification of the active site sulfur-moie...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093659/ https://ncbi.nlm.nih.gov/pubmed/21240419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0ob01050b |
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