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Variable effects of the conserved RNA hairpin element upon 3' end processing of histone pre-mRNA in vitro.
We have studied the requirements for efficient histone-specific RNA 3' processing in nuclear extract from mammalian tissue culture cells. Processing is strongly impaired by mutations in the pre-mRNA spacer element that reduce the base-pairing potential with U7 RNA. Moreover, by exchanging the h...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1993
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309364/ https://ncbi.nlm.nih.gov/pubmed/8479907 |
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