Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi

The balance between stem cell self-renewal and differentiation is precisely controlled to ensure tissue homeostasis and prevent tumorigenesis. Here we use genome-wide transgenic RNAi to identify 620 genes potentially involved in controlling this balance in Drosophila neuroblasts. We quantify all phe...

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Detalhes bibliográficos
Main Authors: Neumüller, Ralph A., Richter, Constance, Fischer, Anja, Novatchkova, Maria, Neumüller, Klaus G., Knoblich, Juergen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093620/
https://ncbi.nlm.nih.gov/pubmed/21549331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.02.022
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