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Structural and Mechanical Analysis of Tectorial Membrane Tecta Mutants

The tectorial membrane (TM) is an extracellular matrix of the cochlea whose prominent role in hearing has been demonstrated through mutation studies. The C1509G mutation of the Tecta gene, which encodes for the α-tectorin protein, leads to hearing loss. The heterozygote TM only attaches to the first...

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Autori principali: Gueta, Rachel, Levitt, Jonathan, Xia, Anping, Katz, Ori, Oghalai, John S., Rousso, Itay
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093563/
https://ncbi.nlm.nih.gov/pubmed/21575588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.024
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