Structural and Mechanical Analysis of Tectorial Membrane Tecta Mutants

The tectorial membrane (TM) is an extracellular matrix of the cochlea whose prominent role in hearing has been demonstrated through mutation studies. The C1509G mutation of the Tecta gene, which encodes for the α-tectorin protein, leads to hearing loss. The heterozygote TM only attaches to the first...

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Bibliografiske detaljer
Main Authors: Gueta, Rachel, Levitt, Jonathan, Xia, Anping, Katz, Ori, Oghalai, John S., Rousso, Itay
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2011
Fag:
Spectroscopy, Imaging, and Other Techniques
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093563/
https://ncbi.nlm.nih.gov/pubmed/21575588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.024
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