EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding

EBV nuclear antigen 2 (EBNA2) and EBV nuclear antigen LP (EBNALP) are critical for B-lymphocyte transformation to lymphoblastoid cell lines (LCLs). EBNA2 activates transcription through recombination signal-binding immunoglobulin κJ region (RBPJ), a transcription factor associated with NCoR repressi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Portal, Daniel, Zhao, Bo, Calderwood, Michael A., Sommermann, Thomas, Johannsen, Eric, Kieff, Elliott
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093489/
https://ncbi.nlm.nih.gov/pubmed/21518914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104991108
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