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Repurposing lipoic acid changes electron flow in two important metabolic pathways of Escherichia coli
In bacteria, cysteines of cytoplasmic proteins, including the essential enzyme ribonucleotide reductase (RNR), are maintained in the reduced state by the thioredoxin and glutathione/glutaredoxin pathways. An Escherichia coli mutant lacking both glutathione reductase and thioredoxin reductase cannot...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093452/ https://ncbi.nlm.nih.gov/pubmed/21521794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105429108 |
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