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Multiple Aggregates and Aggresomes of C-Terminal Truncated Human αA-Crystallins in Mammalian Cells and Protection by αB-Crystallin

BACKGROUND: Cleavage of 11 (αA162), 5 (αA168) and 1 (αA172) residues from the C-terminus of αA-crystallin creates structurally and functionally different proteins. The formation of these post-translationally modified αA-crystallins is enhanced in diabetes. In the present study, the fate of the trunc...

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Bibliografske podrobnosti
Main Authors: Raju, Ilangovan, Kumarasamy, Anbarasu, Abraham, Edathara C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093407/
https://ncbi.nlm.nih.gov/pubmed/21589881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019876
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