Distinct Roles of Bcl-2 and Bcl-Xl in the Apoptosis of Human Bone Marrow Mesenchymal Stem Cells during Differentiation

BACKGROUND: Adult mesenchymal stem cells (MSCs) can be maintained over extended periods of time before activation and differentiation. Little is known about the programs that sustain the survival of these cells. PRINCIPAL FINDINGS: Undifferentiated adult human MSCs (hMSCs) did not undergo apoptosis...

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Detalhes bibliográficos
Main Authors: Oliver, Lisa, Hue, Erika, Rossignol, Julien, Bougras, Gwenola, Hulin, Philippe, Naveilhan, Philippe, Heymann, Dominique, Lescaudron, Laurent, Vallette, François M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093403/
https://ncbi.nlm.nih.gov/pubmed/21589877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019820
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