Hypoxia and Prostaglandin E Receptor 4 Signalling Pathways Synergise to Promote Endometrial Adenocarcinoma Cell Proliferation and Tumour Growth

The prostaglandin endoperoxide synthase (PTGS) pathway is a potent driver of tumour development in humans by enhancing the biosynthesis and signalling of prostaglandin (PG) E(2). PTGS2 expression and PGE(2) biosynthesis is elevated in endometrial adenocarcinoma, however the mechanism whereby PTGS an...

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Detalhes bibliográficos
Main Authors: Catalano, Rob D., Wilson, Martin R., Boddy, Sheila C., McKinlay, Andrew T. M., Sales, Kurt J., Jabbour, Henry N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093383/
https://ncbi.nlm.nih.gov/pubmed/21589857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019209
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