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Hypoxia and Prostaglandin E Receptor 4 Signalling Pathways Synergise to Promote Endometrial Adenocarcinoma Cell Proliferation and Tumour Growth

The prostaglandin endoperoxide synthase (PTGS) pathway is a potent driver of tumour development in humans by enhancing the biosynthesis and signalling of prostaglandin (PG) E(2). PTGS2 expression and PGE(2) biosynthesis is elevated in endometrial adenocarcinoma, however the mechanism whereby PTGS an...

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書誌詳細
主要な著者: Catalano, Rob D., Wilson, Martin R., Boddy, Sheila C., McKinlay, Andrew T. M., Sales, Kurt J., Jabbour, Henry N.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093383/
https://ncbi.nlm.nih.gov/pubmed/21589857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019209
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