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Knockdown of NPY expression in the dorsomedial hypothalamus promotes development of brown adipocytes and prevents diet-induced obesity

Hypothalamic neuropeptide Y (NPY) has been implicated in control of energy balance, but the physiological importance of NPY in the dorsomedial hypothalamus (DMH) remains unclear. Here we report that knockdown of NPY expression in the DMH by adeno-associated virus-mediated RNAi reduced fat depots in...

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Bibliografische gegevens
Hoofdauteurs: Chao, Pei-Ting, Yang, Liang, Aja, Susan, Moran, Timothy H., Bi, Sheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093161/
https://ncbi.nlm.nih.gov/pubmed/21531339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.02.019
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