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Knockdown of NPY expression in the dorsomedial hypothalamus promotes development of brown adipocytes and prevents diet-induced obesity

Hypothalamic neuropeptide Y (NPY) has been implicated in control of energy balance, but the physiological importance of NPY in the dorsomedial hypothalamus (DMH) remains unclear. Here we report that knockdown of NPY expression in the DMH by adeno-associated virus-mediated RNAi reduced fat depots in...

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Bibliografske podrobnosti
Main Authors: Chao, Pei-Ting, Yang, Liang, Aja, Susan, Moran, Timothy H., Bi, Sheng
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093161/
https://ncbi.nlm.nih.gov/pubmed/21531339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.02.019
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