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The Dbp5 cycle at the nuclear pore complex during mRNA export II: nucleotide cycling and mRNP remodeling by Dbp5 are controlled by Nup159 and Gle1

Essential messenger RNA (mRNA) export factors execute critical steps to mediate directional transport through nuclear pore complexes (NPCs). At cytoplasmic NPC filaments, the ATPase activity of DEAD-box protein Dbp5 is activated by inositol hexakisphosphate (IP(6))-bound Gle1 to mediate remodeling o...

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Detalhes bibliográficos
Main Authors: Noble, Kristen N., Tran, Elizabeth J., Alcázar-Román, Abel R., Hodge, Christine A., Cole, Charles N., Wente, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093122/
https://ncbi.nlm.nih.gov/pubmed/21576266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2040611
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